Subacute pyridostigmine exposure increases heart rate recovery and cardiac parasympathetic tone in rats
نویسندگان
چکیده
منابع مشابه
Noninvasive assessment of cardiac parasympathetic function: postexercise heart rate recovery or heart rate variability?
Martin Buchheit, Yves Papelier, Paul B. Laursen, and Saı̈d Ahmaidi Laboratoire de Recherche, Faculté des Sciences du Sport, Université de Picardie Jules Verne, Amiens, France; Faculté de médecine Kremlin-Bicêtre, Explorations Fonctionnelles Multidisciplinaires, Hôpital Antoine-Béclère, Clamart, France; Institut National de Recherche en Informatique et en Automatique, Rocquencourt-Projet Sisyphe,...
متن کاملCholinergic stimulation with pyridostigmine increases heart rate variability and baroreflex sensitivity in rats.
OBJECTIVE Impaired parasympathetic modulation increases the risk for sudden death in patients with heart diseases. Therefore, cholinergic stimulation may have a potential protective role. The aim of this study was to verify the effects of pyridostigmine bromide, a reversible cholinesterase inhibitor, on heart rate (HR), blood pressure (BP), HR and BP variability, and baroreflex sensitivity (BS)...
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Heart failure (HF) is characterized by elevated sympathetic activity and reduced parasympathetic control of the heart. Experimental evidence suggests that the increase in parasympathetic function can be a therapeutic alternative to slow HF evolution. The parasympathetic neurotransmission can be improved by acetylcholinesterase inhibition. We investigated the long-term (4 wk) effects of the acet...
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It is well known that the neuronal projections from the brain to the heart strongly influence cardiac function, and an abnormal activity has been implicated in diseases such as cardiac arrhythmia and sudden infant death syndrome. This short review describes recent advances focused on the neurobiology of cardiac vagal neurons, utilizing cellular techniques.
متن کاملEffect of acetylcholinesterase inhibition with pyridostigmine on cardiac parasympathetic function in sedentary adults and trained athletes.
Heart rate variability and postexercise heart rate recovery are used to assess cardiac parasympathetic tone in human studies, but in some cases these indexes appear to yield discordant information. We utilized pyridostigmine, an acetylcholinesterase inhibitor that selectively augments the parasympathetic efferent signal, to further characterize parasympathetic regulation of rest and postexercis...
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ژورنال
عنوان ژورنال: Clinical and Experimental Pharmacology and Physiology
سال: 2017
ISSN: 0305-1870
DOI: 10.1111/1440-1681.12773